Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes.

  title={Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes.},
  author={Koji Okamoto and Janet M. Shaw},
  journal={Annual review of genetics},
Mitochondria form dynamic tubular networks that continually change their shape and move throughout the cell. In eukaryotes, these organellar gymnastics are controlled by numerous pathways that preserve proper mitochondrial morphology and function. The best understood of these are the fusion and fission pathways, which rely on conserved GTPases and their binding partners to regulate organelle connectivity and copy number in healthy cells and during apoptosis. In budding yeast, mitochondrial… CONTINUE READING
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