Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy study.

@article{Picard2013MitochondrialMT,
  title={Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy study.},
  author={Martin Picard and K Ian White and Douglass Matthew Turnbull},
  journal={Journal of applied physiology},
  year={2013},
  volume={114 2},
  pages={161-71}
}
Dynamic remodeling of mitochondrial morphology through membrane dynamics are linked to changes in mitochondrial and cellular function. Although mitochondrial membrane fusion/fission events are frequent in cell culture models, whether mitochondrial membranes dynamically interact in postmitotic muscle fibers in vivo remains unclear. Furthermore, a quantitative assessment of mitochondrial morphology in intact muscle is lacking. Here, using electron microscopy (EM), we provide evidence of… CONTINUE READING

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Muscle mitochondrial ultrastructure: new insights into morphological divergences.

Journal of applied physiology • 2013
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