Mitochondrial metabolite transport.

  title={Mitochondrial metabolite transport.},
  author={Ferdinando Palmieri and Ciro Leonardo Pierri},
  journal={Essays in biochemistry},
The flux of a variety of metabolites, nucleotides and coenzymes across the inner membrane of mitochondria is catalysed by a nuclear-coded superfamily of secondary transport proteins called MCs (mitochondrial carriers). The importance of MCs is demonstrated by their wide distribution in all eukaryotes, their role in numerous metabolic pathways and cell functions, and the identification of several diseases caused by alterations of their genes. MCs can easily be recognized in databases thanks to… CONTINUE READING

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