Mitochondrial metabolism and energy sensing in tumor progression.

Abstract

Energy homeostasis is pivotal for cell fate since metabolic regulation, cell proliferation and death are strongly dependent on the balance between catabolic and anabolic pathways. In particular, metabolic and energetic changes have been observed in cancer cells even before the discovery of oncogenes and tumor suppressors, but have been neglected for a long… (More)
DOI: 10.1016/j.bbabio.2017.02.006

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