Mitochondrial malate dehydrogenase lowers leaf respiration and alters photorespiration and plant growth in Arabidopsis.

@article{Tomaz2010MitochondrialMD,
  title={Mitochondrial malate dehydrogenase lowers leaf respiration and alters photorespiration and plant growth in Arabidopsis.},
  author={Tiago Tomaz and Matthieu Bagard and Itsara Pracharoenwattana and Pernilla Lind{\'e}n and Chun Pong Lee and Adam J. Carroll and Elke Str{\"o}her and Steven M Smith and Per Gardestr{\"o}m and A Harvey Millar},
  journal={Plant physiology},
  year={2010},
  volume={154 3},
  pages={1143-57}
}
Malate dehydrogenase (MDH) catalyzes a reversible NAD(+)-dependent-dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments. To explore the role of mitochondrial MDH (mMDH) in Arabidopsis (Arabidopsis thaliana), knockout single and double mutants for the highly expressed mMDH1 and lower expressed mMDH2 isoforms were constructed and analyzed. A mmdh1mmdh2 mutant has no detectable mMDH activity but is viable, albeit small and slow growing… CONTINUE READING