Mitochondrial ion channels.

  title={Mitochondrial ion channels.},
  author={Brian O'Rourke},
  journal={Annual review of physiology},
In work spanning more than a century, mitochondria have been recognized for their multifunctional roles in metabolism, energy transduction, ion transport, inheritance, signaling, and cell death. Foremost among these tasks is the continuous production of ATP through oxidative phosphorylation, which requires a large electrochemical driving force for protons across the mitochondrial inner membrane. This process requires a membrane with relatively low permeability to ions to minimize energy… CONTINUE READING
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