Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1.

@article{Roeder1998MitochondrialII,
  title={Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1.},
  author={Amy D Roeder and Greg J. Hermann and Brian Robert Keegan and Steve Thatcher and Janet M. Shaw},
  journal={Molecular biology of the cell},
  year={1998},
  volume={9 4},
  pages={917-30}
}
In wild-type yeast mitochondrial inheritance occurs early in the cell cycle concomitant with bud emergence. Cells lacking the PTC1 gene initially produce buds without a mitochondrial compartment; however, these buds later receive part of the mitochondrial network from the mother cell. Thus, the loss of PTC1 causes a delay, but not a complete block, in mitochondrial transport. PTC1 encodes a serine/threonine phosphatase in the high-osmolarity glycerol response (HOG) pathway. The mitochondrial… CONTINUE READING