Mitochondrial haplogroups are associated with severity of diabetic retinopathy.

  title={Mitochondrial haplogroups are associated with severity of diabetic retinopathy.},
  author={Christopher B. Estopinal and Isaac M. Chocron and Megan B. Parks and Emily A Wade and Rachel M Roberson and Lucia Goodwin Burgess and Milam Brantley and David C. Samuels},
  journal={Investigative ophthalmology & visual science},
  volume={55 9},
PURPOSE To determine if specific mitochondrial haplogroups associate with nonproliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR). METHODS Deidentified medical records for Caucasian patients with diabetic retinopathy (DR; 153 NPDR and 138 PDR) were obtained from BioVU, Vanderbilt University's electronic, deidentified DNA databank. An independent cohort of Caucasian patients with DR (44 NPDR and 57 PDR) from the Vanderbilt Eye Institute (VEI) was used for… CONTINUE READING