Mitochondrial haplogroup U is associated with a reduced risk to develop exfoliation glaucoma in the German population

@inproceedings{Wolf2009MitochondrialHU,
  title={Mitochondrial haplogroup U is associated with a reduced risk to develop exfoliation glaucoma in the German population},
  author={Christiane Wolf and Eugen Gramer and Bertram M{\"u}ller-Myhsok and Francesca Pasutto and Bernd Wissinger and Nicole Weisschuh},
  booktitle={BMC Genetics},
  year={2009}
}
Various lines of evidence demonstrate the involvement of mitochondrial dysfunction in the pathogenesis of glaucoma. Therefore, mitochondrial DNA is a promising candidate for genetic susceptibility studies on glaucoma. To test the hypothesis that mitochondrial haplogroups influence the risk to develop glaucoma, we genotyped 12 single-nucleotide polymorphisms that define the European mitochondrial DNA haplogroups in healthy controls and two German patient cohorts with either exfoliation glaucoma… CONTINUE READING

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