Mitochondrial genotype segregation and effects during mammalian development: applications to biotechnology.

@article{Smith2000MitochondrialGS,
  title={Mitochondrial genotype segregation and effects during mammalian development: applications to biotechnology.},
  author={Lawrence Charles Smith and Vilceu Bordignon and Joaquim Mansano Garcia and Fl{\'a}vio Vieira Meirelles},
  journal={Theriogenology},
  year={2000},
  volume={53 1},
  pages={35-46}
}
Mitochondria are endosymbiotic organelles responsible for energy production in practically every eukaryotic cell. Their uniparental fashion of inheritance, maternally inherited in mammals, and the homogeneity of mitochondrial DNA (mtDNA) within individuals and matrilineages, are biological phenomena that remain unexplained. This paper reviews some of the recent findings on mitochondrial influences on the manner in which embryos develop and how their genotypes are inherited in mammals, with… CONTINUE READING