Mitochondrial fission/fusion dynamics and apoptosis.

@article{Sheridan2010MitochondrialFD,
  title={Mitochondrial fission/fusion dynamics and apoptosis.},
  author={Clare Sheridan and Seamus J. Martin},
  journal={Mitochondrion},
  year={2010},
  volume={10 6},
  pages={
          640-8
        }
}
Mitochondria play an important role in the progression of apoptosis through the release of pro-apoptotic factors, such as cytochrome c, from the mitochondrial intermembrane space. During this process, mitochondrial networks are dramatically reorganised from long filamentous interconnected tubules into small punctate spheres. Whether remodelling of mitochondrial networks is necessary for apoptosis-associated cytochrome c release, or merely an accompanying process, has been a subject of debate… CONTINUE READING
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