Mitochondrial ferritin deficiency reduces male fertility in mice.


Mitochondrial ferritin (FtMt) is a functional ferritin targeted to mitochondria that is highly expressed in the testis. To investigate the role of FtMt in the testis we set up a series of controlled matings between FtMt gene-deletion mice (FtMt-/-) with FtMt+/+ mice. We found that the number of newborns per litter and the fertility rate were strongly… (More)
DOI: 10.1071/RD16348


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@article{Maccarinelli2017MitochondrialFD, title={Mitochondrial ferritin deficiency reduces male fertility in mice.}, author={Federica Maccarinelli and Maria Regoni and Fernando Carmona and Maura Poli and Esther G. Meyron-Holtz and Paolo Arosio}, journal={Reproduction, fertility, and development}, year={2017}, volume={29 10}, pages={2005-2010} }