Mitochondrial dysfunction in an animal model of hyperoxaluria: a prophylactic approach with fucoidan.

@article{Veena2008MitochondrialDI,
  title={Mitochondrial dysfunction in an animal model of hyperoxaluria: a prophylactic approach with fucoidan.},
  author={Coothan Kandaswamy Veena and Anthony Josephine and Sreenivasan P. Preetha and Nachiappa Ganesh Rajesh and Palaninathan Varalakshmi},
  journal={European journal of pharmacology},
  year={2008},
  volume={579 1-3},
  pages={330-6}
}
Oxalate/calcium oxalate toxicity is mediated through generation of reactive oxygen species in a process that partly depends upon events that induce mitochondrial damage. Mitochondrial dysfunction is an important event favoring stone formation. The objective of the present study was to investigate whether mitochondria is a target for oxalate/calcium oxalate and the plausible role of naturally occurring glycosaminoglycans from edible seaweed, fucoidan in ameliorating mitochondrial damage. Male… CONTINUE READING

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