Mitochondrial dysfunction as a central event for mechanisms underlying insulin resistance: the roles of long chain fatty acids.

@article{Bakar2015MitochondrialDA,
  title={Mitochondrial dysfunction as a central event for mechanisms underlying insulin resistance: the roles of long chain fatty acids.},
  author={Mohamad Hafizi Abu Bakar and Cheng Kian Kai and Wan Najihah Wan Hassan and Mohamad Roji Sarmidi and Harisun Yaakob and Hasniza Zaman Huri},
  journal={Diabetes/metabolism research and reviews},
  year={2015},
  volume={31 5},
  pages={
          453-75
        }
}
Insulin resistance is characterized by hyperglycaemia, dyslipidaemia and oxidative stress prior to the development of type 2 diabetes mellitus. To date, a number of mechanisms have been proposed to link these syndromes together, but it remains unclear what the unifying condition that triggered these events in the progression of this metabolic disease. There have been a steady accumulation of data in numerous experimental studies showing the strong correlations between mitochondrial dysfunction… CONTINUE READING
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Molecular mechanism of insulin resistance in obesity and type 2 diabetes

  • K Choi, YB Kim
  • Korean J Intern Med
  • 2010
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