Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.

  title={Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.},
  author={Satish Srinivasan and Manti Guha and Anna Kashina and Narayan G Avadhani},
  journal={Biochimica et biophysica acta. Bioenergetics},
  volume={1858 8},
Mitochondrial dysfunction is a hallmark of many diseases. The retrograde signaling initiated by dysfunctional mitochondria can bring about global changes in gene expression that alters cell morphology and function. Typically, this is attributed to disruption of important mitochondrial functions, such as ATP production, integration of metabolism, calcium homeostasis and regulation of apoptosis. Recent studies showed that in addition to these factors, mitochondrial dynamics might play an… CONTINUE READING
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Mitochondria in cancer.

Biochimica et biophysica acta. Bioenergetics • 2017
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Proteome Res 2016 Feb 5;15(2):608-18

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