Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure.

  title={Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure.},
  author={Marc Liesa and Orian S Shirihai},
  journal={Cell metabolism},
  volume={17 4},
Mitochondrial fusion, fission, and mitophagy form an essential axis of mitochondrial quality control. However, quality control might not be the only task carried out by mitochondrial dynamics. Recent studies link mitochondrial dynamics to the balance between energy demand and nutrient supply, suggesting changes in mitochondrial architecture as a mechanism for bioenergetic adaptation to metabolic demands. By favoring either connected or fragmented architectures, mitochondrial dynamics regulates… CONTINUE READING
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