Mitochondrial dynamics and Ca2+ signaling.

  title={Mitochondrial dynamics and Ca2+ signaling.},
  author={Gy{\"o}rgy Szabadkai and Anna Maria Simoni and Katiuscia Bianchi and Diego De Stefani and Sara Leo and Mariusz Roman Wieckowski and Rosario Rizzuto},
  journal={Biochimica et biophysica acta},
  volume={1763 5-6},
Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2… CONTINUE READING

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