Mitochondrial dynamics, cell death and the pathogenesis of Parkinson’s disease

@article{Beler2010MitochondrialDC,
  title={Mitochondrial dynamics, cell death and the pathogenesis of Parkinson’s disease},
  author={Hansruedi B{\"u}eler},
  journal={Apoptosis},
  year={2010},
  volume={15},
  pages={1336-1353}
}
The structure and function of the mitochondrial network is regulated by mitochondrial biogenesis, fission, fusion, transport and degradation. A well-maintained balance of these processes (mitochondrial dynamics) is essential for neuronal signaling, plasticity and transmitter release. Core proteins of the mitochondrial dynamics machinery play important roles in the regulation of apoptosis, and mutations or abnormal expression of these factors are associated with inherited and age-dependent… CONTINUE READING
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