Mitochondrial distribution and function in oocytes and early embryos.

  title={Mitochondrial distribution and function in oocytes and early embryos.},
  author={Barry D. Bavister and Jayne M Squirrell},
  journal={Human reproduction},
  volume={15 Suppl 2},
Active mitochondria relocate during oocyte maturation or fertilization in several species. Detailed studies with hamster oocytes and early embryos reveal a pattern of active mitochondria migrating to surround the pronuclei to form a pattern that persists through the early cleavage stages. Although the functional significance of this relocation is unknown, it appears to be an important part of normal development in hamsters. Treatments that disrupt embryo development in vitro (such as the… CONTINUE READING
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