Mitochondrial diseases in man and mouse.


Over the past 10 years, mitochondrial defects have been implicated in a wide variety of degenerative diseases, aging, and cancer. Studies on patients with these diseases have revealed much about the complexities of mitochondrial genetics, which involves an interplay between mutations in the mitochondrial and nuclear genomes. However, the pathophysiology of… (More)


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@article{Wallace1999MitochondrialDI, title={Mitochondrial diseases in man and mouse.}, author={Dolores Wallace}, journal={Science}, year={1999}, volume={283 5407}, pages={1482-8} }