Mitochondrial disease

@article{Schapira2006MitochondrialD,
  title={Mitochondrial disease},
  author={A. Schapira},
  journal={The Lancet},
  year={2006},
  volume={368},
  pages={70-82}
}
Defects of mitochondrial metabolism cause a wide range of human diseases that include examples from all medical subspecialties. This review updates the topic of mitochondrial diseases by reviewing the most important recent advances in this area. The factors influencing inheritance, maintenance and replication of mtDNA are reviewed and the genotype-phenotype of mtDNA disorders has been expanded, with new insights into epidemiology, pathogenesis and its role in ageing. Recently identified nuclear… Expand
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