Mitochondrial damage: an important mechanism of ambient PM2.5 exposure-induced acute heart injury in rats.

@article{Li2015MitochondrialDA,
  title={Mitochondrial damage: an important mechanism of ambient PM2.5 exposure-induced acute heart injury in rats.},
  author={Ruijin Li and Xiaojing Kou and Hong Geng and Jingfang Xie and Jingjing Tian and Zongwei Cai and Chuan Dong},
  journal={Journal of hazardous materials},
  year={2015},
  volume={287},
  pages={392-401}
}
Epidemiological studies suggested that ambient fine particulate matter (PM2.5) exposure was associated with cardiovascular disease. However, the underlying mechanism, especially the mitochondrial damage mechanism, of PM2.5-induced heart acute injury is still unclear. In this study, the alterations of mitochondrial morphology and mitochondrial fission/fusion gene expression, oxidative stress, calcium homeostasis and inflammation in hearts of rats exposed to PM2.5 with different dosages (0.375, 1… CONTINUE READING
16 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…