Mitochondrial creatine kinase in human health and disease.


Mitochondrial creatine kinase (MtCK), together with cytosolic creatine kinase isoenzymes and the highly diffusible CK reaction product, phosphocreatine, provide a temporal and spatial energy buffer to maintain cellular energy homeostasis. Mitochondrial proteolipid complexes containing MtCK form microcompartments that are involved in channeling energy in… (More)


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@article{Schlattner2006MitochondrialCK, title={Mitochondrial creatine kinase in human health and disease.}, author={Uwe Schlattner and Malgorzata Tokarska-Schlattner and Theo Wallimann}, journal={Biochimica et biophysica acta}, year={2006}, volume={1762 2}, pages={164-80} }