Mitochondrial complex II, a novel target for anti-cancer agents.

@article{Kluckova2013MitochondrialCI,
  title={Mitochondrial complex II, a novel target for anti-cancer agents.},
  author={Katarina Kluckova and Ayanachew Bezawork-Geleta and Jakub Rohlena and Lanfeng Dong and Jiri Neuzil},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1827 5},
  pages={
          552-64
        }
}
With the arrival of the third millennium, in spite of unprecedented progress in molecular medicine, cancer remains as untamed as ever. The complexity of tumours, dictating the potential response of cancer cells to anti-cancer agents, has been recently highlighted in a landmark paper by Weinberg and Hanahan on hallmarks of cancer [1]. Together with the recently published papers on the complexity of tumours in patients and even within the same tumour (see below), the cure for this pathology seems… CONTINUE READING
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