Mitochondrial capacity, muscle endurance, and low energy in friedreich ataxia.

  title={Mitochondrial capacity, muscle endurance, and low energy in friedreich ataxia.},
  author={Hannah M Bossie and T. Bradley Willingham and Robbi A Van Schoick and Patrick J. O'Connor and Kevin K McCully},
  journal={Muscle & nerve},
  volume={56 4},
INTRODUCTION In this study we noninvasively evaluated skeletal muscle mitochondrial capacity, muscle-specific endurance, and energy/fatigue feelings in persons with Friedreich ataxia (FRDA) and able-bodied controls (AB). METHODS Forearm mitochondrial capacity was measured in FRDA (n = 16) and AB (n = 10) study participants using the rate of recovery of oxygen consumption after electrical stimulation with near-infrared spectroscopy. Mechanomyography (MMG) assessed muscle endurance after… CONTINUE READING
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