Mitochondrial and nuclear genes present conflicting portraits of human origins.

@article{Hey1997MitochondrialAN,
  title={Mitochondrial and nuclear genes present conflicting portraits of human origins.},
  author={Jody Hey},
  journal={Molecular biology and evolution},
  year={1997},
  volume={14 2},
  pages={166-72}
}
  • Jody Hey
  • Published 1997 in Molecular biology and evolution
Human mitochondrial DNA (mtDNA) sequences reveal an abundance of polymorphic sites in which the frequencies of the segregating bases are very different. A typical polymorphism involves one base at low frequency and the other base at high frequency. In contrast, nuclear gene data sets tend to show an excess of polymorphisms in which both segregating bases are at intermediate frequencies. A new statistical test of this difference finds significant differences between mtDNA and nuclear gene data… CONTINUE READING

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