Mitochondrial and metabolic remodeling during reprogramming and differentiation of the reprogrammed cells.


Reprogramming is one of the most essential areas of research in stem cell biology. Despite this importance, the mechanism and correlates of reprogramming remain largely unknown. In this study, we investigated the cytoplasmic remodeling and changes in metabolism that occur during reprogramming and differentiation of pluripotent stem cells. Specifically, we… (More)
DOI: 10.1089/scd.2014.0561


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