Mitochondrial adenylate kinase (AK2) from bovine heart. Homology with the cytosolic isoenzyme in the catalytic region.

Abstract

The adenylate kinase isoenzyme located in the intermembrane space of mitochondria, AK2, is a monomeric protein of Mr 30000 which catalyzes the reaction ATP + AMP + AMP in equilibrium 2 ADP. The protein was reduced and S-carboxymethylated with iodo[14C2]acetate. Using a Laursen sequenator, the N-terminal sequence of S-carboxymethylated AK2 was determined as… (More)

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@article{Frank1984MitochondrialAK, title={Mitochondrial adenylate kinase (AK2) from bovine heart. Homology with the cytosolic isoenzyme in the catalytic region.}, author={Rainer W. Frank and Michael Trosin and Alfredo G Tomasselli and Georg E. Schulz and R. Heiner Schirmer}, journal={European journal of biochemistry}, year={1984}, volume={141 3}, pages={629-36} }