Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy.

@article{Abel2011MitochondrialAT,
  title={Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy.},
  author={E. Dale Abel and Torsten Doenst},
  journal={Cardiovascular research},
  year={2011},
  volume={90 2},
  pages={234-42}
}
Cardiac hypertrophy is a stereotypic response of the heart to increased workload. The nature of the workload increase may vary depending on the stimulus (repetitive, chronic, pressure, or volume overload). If the heart fully adapts to the new loading condition, the hypertrophic response is considered physiological. If the hypertrophic response is associated with the ultimate development of contractile dysfunction and heart failure, the response is considered pathological. Although divergent… CONTINUE READING

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