Mitochondrial ROS fire up T cell activation.

  title={Mitochondrial ROS fire up T cell activation.},
  author={Michael P Murphy and Richard M Siegel},
  volume={38 2},
Metabolic reprogramming has emerged as an important feature of immune cell activation. Two new studies, including Sena et al. (2013) in this issue of Immunity, identify mitochondrial reactive oxygen species (ROS) arising from metabolic reprogramming as signaling molecules in T cell activation.