Mitochondrial Pathogenesis

Abstract

Mitochondrial diseases, such as MELAS, MERRF, and CPEO syn-<lb>dromes, are associated with specific point mutations or large-scale deletions of<lb>mitochondrial DNA (mtDNA), which impair mitochondrial respiratory func-<lb>tions and result in decreased production of ATP in affected tissues. Recently,<lb>mitochondria have been recognized to act as key players… (More)
DOI: 10.1007/978-3-662-41088-2

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