Mitochondrial P450s.

  title={Mitochondrial P450s.},
  author={Tsuneo Omura},
  journal={Chemico-biological interactions},
  volume={163 1-2},
  • Tsuneo Omura
  • Published 2006 in Chemico-biological interactions
Cytochrome P450 was first found in the microsomes from animal tissues, and then the presence of P450 in mitochondria was reported for the steroidogenic organs, adrenal gland and gonads. Three forms of mitochondrial P450 (11A, 11B1, and 11B2) were purified from these organs and their functions in steroid hormone biosynthesis were confirmed. Later studies showed the presence of several other forms of P450 (24A, 27A, 27B, and 27C) in the mitochondria of various non-steroidogenic organs including… CONTINUE READING


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