Mitochondrial Mutations

  title={Mitochondrial Mutations},
  author={Nichola Zoe Lax and Douglass Matthew Turnbull and Amy Katherine Reeve},
  booktitle={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
Mutations in mitochondrial DNA cause a number of neurological diseases with defined neuropathology; however, mutations in this genome have also been found to be important in a number of more common neurodegenerative diseases. In this review, the authors discuss the importance of mitochondrial DNA mutations in a number of different diseases and speculate how such mutations could lead to cell loss. Increasing our understanding of how mitochondrial DNA mutations affect mitochondrial metabolism and… CONTINUE READING

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