Mitochondrial Metabolic Inhibition and Cardioprotection

  title={Mitochondrial Metabolic Inhibition and Cardioprotection},
  author={Sung Ryul Lee and Jin Han},
  journal={Korean Circulation Journal},
  pages={168 - 170}
Reperfusion is needed to initiate reflow of blood in cardiac arrest triggered by surgical intervention or pathologically-induced cardiac ischemia. However, subsequent reperfusion may lead not only to the recovery of ischemic cardiac tissue, but also to the paradoxical phenomenon of myocardial ischemia/reperfusion (IR) injury, including protracted organ recovery, myocardial stunning, and acute myocardial infarction (MI). Mortality due to acute MI remains substantial, and the prevalence of MI… 
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