Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia.

@article{Kuo2015MitochondrialLP,
  title={Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia.},
  author={Chan-Yen Kuo and Yi-Chieh Chiu and Alan Yueh-Luen Lee and Tsong-Long Hwang},
  journal={Mitochondrion},
  year={2015},
  volume={23},
  pages={7-16}
}
Apoptosis of cardiomyocytes, under ischemic conditions, has been identified as an essential process in the progression of heart failure. Under hypoxic conditions, mitochondria can become a threat to the cell because of their capacity to generate reactive oxygen species (ROS). As ROS appear to have a critical role in heart failure, there has been… CONTINUE READING