Mitochondrial Localization of Vitamin D Receptor in Human Platelets and Differentiated Megakaryocytes

@inproceedings{Silvagno2010MitochondrialLO,
  title={Mitochondrial Localization of Vitamin D Receptor in Human Platelets and Differentiated Megakaryocytes},
  author={Francesca Silvagno and Enrico De Vivo and Angelo Attanasio and Valentina Patrizia Gallo and Gianna Mazzucco and Gianpiero Pescarmona},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Like other steroid hormones, vitamin D elicits both transcriptional events and rapid non genomic effects. Vitamin D receptor (VDR) localization and mechanisms of VDR-triggered non genomic responses are still controversial. Although anticoagulant effects of vitamin D have been reported and VDR signalling has been characterized in monocytes and vascular cells, nothing is known about VDR expression and functions in human platelets, anucleated fragments of megakaryocytes which are known… CONTINUE READING
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