Mitochondrial Fusion Is Essential for Steroid Biosynthesis

@inproceedings{Duarte2012MitochondrialFI,
  title={Mitochondrial Fusion Is Essential for Steroid Biosynthesis},
  author={Alejandra Hern{\'a}ndez Duarte and Cecilia Poderoso and Mariana Cooke and Gast{\'o}n Soria and Fabiana Cornejo Maciel and Vanesa Gottifredi and Ernesto Jorge Podest{\'a}},
  booktitle={PloS one},
  year={2012}
}
Although the contribution of mitochondrial dynamics (a balance in fusion/fission events and changes in mitochondria subcellular distribution) to key biological process has been reported, the contribution of changes in mitochondrial fusion to achieve efficient steroid production has never been explored. The mitochondria are central during steroid synthesis and different enzymes are localized between the mitochondria and the endoplasmic reticulum to produce the final steroid hormone, thus… CONTINUE READING

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