Corpus ID: 18702627

Mitochondrial Disease Clinical Manifestations: an Overview General Characteristics of Pediatric and Adult- Onset Disease

@inproceedings{MattmanMitochondrialDC,
  title={Mitochondrial Disease Clinical Manifestations: an Overview General Characteristics of Pediatric and Adult- Onset Disease},
  author={A. Mattman and S. Sirrs and M. Mezei and R. Salvarinova-Zivkovic and M. Alfadhel and Y. Lillquist}
}
Mitochondrial diseases are a heterogeneous group of disorders that can affect multiple organs with varying severity. Symptoms may be acute or chronic with intermittent decompensation. In childhood-onset disease, there is often a history of global developmental delay, while in adulthood the past history may be unremarkable prior to initial presentation. The unique character of mito-chondrial genetics means family history patterns of inheritance may be both maternal and autosomal, making genetic… CONTINUE READING

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