Mitochondrial DNA replication in sea urchin oocytes.

@article{Matsumoto1974MitochondrialDR,
  title={Mitochondrial DNA replication in sea urchin oocytes.},
  author={Lloyd H. Matsumoto and Harumi Kasamatsu and Lajos Pik{\'o} and Jerome Vinograd},
  journal={The Journal of cell biology},
  year={1974},
  volume={63 1},
  pages={
          146-59
        }
}

• Lloyd H. Matsumoto, Harumi Kasamatsu, +1 author Jerome Vinograd
• Published 1974 in The Journal of cell biology

Mitochondrial DNA (mtDNA) replicative intermediates from Strongylocentrotus purpuratus oocytes were isolated by ethidium bromide-CsCl density gradient centrifugation and examined by electron microscopy after formamide spreading. In some experiments, the mtDNA was radioactively labeled by exposing isolated oocytes to [(3)H]thymidine. Oocyte mtDNA replication appears to follow the displacement loop model outlined in mouse L cells. There are differences in detail. The frequency of D-loop DNA is… CONTINUE READING

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