Mitochondrial DNA rearrangements in young onset parkinsonism: two case reports.

Abstract

Parkinson's disease is a nosological entity of unknown origin for which, in some cases, a possible pathogenetic role for mitochondrial dysfunction has been postulated. Two young onset parkinsonian patients with mitochondrial DNA (mtDNA) deletions in skeletal muscle are reported on. Patient 1 also presented with increased blood creatine kinase and lactate… (More)

Topics

2 Figures and Tables

Cite this paper

@article{Siciliano2001MitochondrialDR, title={Mitochondrial DNA rearrangements in young onset parkinsonism: two case reports.}, author={Gabriele Siciliano and M Mancuso and Roberto Ceravolo and Valeria Lombardi and Alfonso Iudice and Ubaldo Bonuccelli}, journal={Journal of neurology, neurosurgery, and psychiatry}, year={2001}, volume={71 5}, pages={685-7} }