Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population

@article{Huerta2005MitochondrialDP,
  title={Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population},
  author={Cecilia Huerta and M Gonz{\'a}lez Castro and Eliecer Coto and Marta Bl{\'a}zquez and Victoria {\'A}lvarez},
  journal={Journal of the Neurological Sciences},
  year={2005},
  volume={236},
  pages={49-54}
}
Mutations in mitochondrial DNA (mtDNA) have been implicated in the development of Parkinson's disease (PD). Mitochondrial function is necessary to supply the energy required for cell metabolism, and mutations in mitochondrial genes should have a deleterious effect in neuronal function. An association between several common mtDNA-polymorphisms and the risk of PD has been described. To test this association among Spanish patients, we genotyped 271 PD-patients and 230 healthy controls for 13… CONTINUE READING

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