Mitochondrial DNA mutations in an outbreak of optic neuropathy in Cuba.

@article{Hirano1994MitochondrialDM,
  title={Mitochondrial DNA mutations in an outbreak of optic neuropathy in Cuba.},
  author={M Hirano and J M Cleary and Alex Mitchell Stewart and Norah S Lincoff and Jeffrey G. Odel and Rosaralis Santiesteban and R Santiago Luis},
  journal={Neurology},
  year={1994},
  volume={44 5},
  pages={843-5}
}
Since October 1991, nearly 51,000 Cubans have been afflicted in an outbreak of optic and peripheral neuropathies. To begin an investigation of the possible role of mitochondrial DNA (mtDNA) mutations in the outbreak, we studied mtDNA from 14 affected and two unaffected Cubans for the 12 mutations associated with Leber's hereditary optic neuropathy. Eleven… CONTINUE READING