Mitochondrial DNA mutations in Japanese patients with optic neuropathy unassociated with a mutation at nucleotide position 11,778

@article{Matsumoto1998MitochondrialDM,
  title={Mitochondrial DNA mutations in Japanese patients with optic neuropathy unassociated with a mutation at nucleotide position 11,778},
  author={Masayuki Matsumoto and Seiji Hayasaka and Yoshihiro Hotta and Keiko Fujiki and Takuro Fujimaki and Misako Takeda and Nobuo Ishida and Shin-ichiro Endo and Atsushi Kanai},
  journal={Journal of Human Genetics},
  year={1998},
  volume={43},
  pages={242-245}
}
AbstractWe examined for mitochondrial DNA (mtDNA) mutations at nucleotide positions(nt) 3460, 14,484, 9438, 9804, and 15,257 in ten Japanese patients with idiopathic optic neuropathy unassociated with a mutation at nt11,778. The mtDNAs were amplified by polymerase chain reaction (PCR), the products were digested with restriction enzymes, and the sizes of… CONTINUE READING