Mitochondrial DNA haplogroups and risk of transient ischaemic attack and ischaemic stroke: a genetic association study

@inproceedings{Chinnery2010MitochondrialDH,
  title={Mitochondrial DNA haplogroups and risk of transient ischaemic attack and ischaemic stroke: a genetic association study},
  author={Patrick F. Chinnery and Hannah R Elliott and Anila Syed and Peter M. Rothwell},
  booktitle={The Lancet Neurology},
  year={2010}
}
BACKGROUND Genetic factors have a role in the pathogenesis of ischaemic stroke, but the main genes involved have yet to be defined. Mitochondrial mechanisms have been implicated in the pathophysiology of acute stroke, but the role of mitochondrial DNA (mtDNA) has not been comprehensively studied. We investigated whether there is an association between mtDNA haplotypes and incidence of stroke. METHODS The major European mtDNA haplogroups were identified in two independent subpopulations (n=950… CONTINUE READING
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Risk variants for atrial fi brillation on chromosome 4 q 25 associate with ischemic stroke

  • S Gretarsdottir, G Thorleifsson, A Manolescu
  • Ann Neurol
  • 2008

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