Mitochondrial DNA and human evolution

@article{Cann1987MitochondrialDA,
  title={Mitochondrial DNA and human evolution},
  author={R. Cann and M. Stoneking and A. Wilson},
  journal={Nature},
  year={1987},
  volume={325},
  pages={31-36}
}
Mitochondrial DNAsfrom 147 people, drawn from five geographic populations have been analysed by restriction mapping. All these mitochondrial DMAs stem from one woman who is postulated to have lived about 200,000 years ago, probably in Africa. All the populations examined except the African population have multiple origins, implying that each area was colonised repeatedly. 
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References

SHOWING 1-10 OF 38 REFERENCES
Human mitochondrial DNA types in two Israeli populations--a comparative study at the DNA level.
TLDR
Variations in human mtDNA restriction endonuclease fragment patterns were investigated in a sample number of 81 Israelis--Jews and Arabs--using total blood cell DNA, finding one of the new types filled a "missing link" originally postulated in a phylogeny of mtDNA human types. Expand
Genetic and fossil evidence for the origin of modern humans.
TLDR
Genetic data on present human population relationships and data from the Pleistocene fossil hominid record are used to compare two contrasting models for the origin of modern humans. Expand
Nucleotide sequence evidence for rapid genotypic shifts in the bovine mitochondrial DNA D-loop
TLDR
The nucleotide sequence of all or part of the D-loop region in 14 maternally related Holstein cows is determined to help answer the question of how individual variant mtDNA molecules resulting from mutational events can come to dominate the large intracellular mtDNA population so rapidly. Expand
Dramatic founder effects in Amerindian mitochondrial DNAs.
Southwestern American Indian (Amerindian) mitochondrial DNAs (mtDNAs) were analyzed with restriction endonucleases and found to contain Asian restriction fragment length polymorphisms (RFLPs) but atExpand
Evolutionary tree for apes and humans based on cleavage maps of mitochondrial DNA.
TLDR
Although this study has given a magnified view of the genetic differences among humans and apes, the possibility of a three-way split among the lineages leading to humans, gorillas, and chimpanzees still deserves serious consideration. Expand
Maternal inheritance of human mitochondrial DNA.
TLDR
The results of this study demonstrate that human mitochondrial DNA is maternally inherited and represents a convenient way to obtain data on mitochondrial DNA variation in both individuals and populations. Expand
Mitochondrial DNA and two perspectives on evolutionary genetics
This essay reviews comparative studies of animal mitochondrial DNA (mtDNA), with emphasis on findings made and ideas developed at Berkeley. It argues that such studies are bringing together twoExpand
Polymorphism in mitochondrial DNA of humans as revealed by restriction endonuclease analysis.
  • W. Brown
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1980
TLDR
The data indicate that individuals differ from a postulated ancestral mtDNA sequence at 0.18% of their base pairs, and suggest that group-specific patterns of cleavage exist. Expand
Polymorphic sites and the mechanism of evolution in human mitochondrial DNA.
TLDR
This example, along with that for the mitochondrial rRNA genes and the nuclear genes coding for mitochondrial ribosomal proteins, provides evidence for coevolution between specific nuclear and mitochondrial genes. Expand
Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms
TLDR
It is found that all non-African populations share a limited number of common haplotypes whereas Africans have predominantly a different haplotype not found in other populations. Expand
...
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3
4
...