Corpus ID: 89428373

Mitochondrial DNA and Inherited Diseases - A Comprehensive Review

@inproceedings{Rv2011MitochondrialDA,
  title={Mitochondrial DNA and Inherited Diseases - A Comprehensive Review},
  author={Geetha Rv and A. Roy and Vishnu Priyav and T. Lakshmi},
  year={2011}
}
Mitochondria are membrane - bound organelles located in the cytoplasm of the cell. They are the sites o f cellular respiration which ultimately generates fuel for the cell's activities. Mitochondria are the only non-nuclear constituents of the cell with their own DNA (mtDNA) and machinery for synthesizing RNA and proteins. Mutations in the mitochondrial genome have been implicated with a wide range of age-related pathologies, cancers, neurodegenerative diseases and in general, processes that… Expand
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