Mitochondrial DNA Variation in the Aboriginal Populations of the Altai‐Baikal Region: Implications for the Genetic History of North Asia and America

@article{Zakharov2004MitochondrialDV,
  title={Mitochondrial DNA Variation in the Aboriginal Populations of the Altai‐Baikal Region: Implications for the Genetic History of North Asia and America},
  author={I. Zakharov and M. Derenko and B. A. Maliarchuk and I. Dambueva and C. Dorzhu and S. Rychkov},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1011}
}
Abstract: The discovery of mtDNA types common to Asians and Amerinds (types A, B, C, and D) forced investigators to search for those nations of Asia which, though not considered the ancestors of the Amerinds, have retained a close genetic resemblance with them. We collected samples and studied the gene pools of the Turkic‐speaking nations of South Siberia: Altaians, Khakassians, Shorians, Tuvinians, Todjins, Tofalars, Sojots, as well as Mongolian‐speaking Buryats. The data indicate that nearly… Expand

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    References

    SHOWING 1-10 OF 35 REFERENCES
    Mitochondrial DNA variation in two South Siberian Aboriginal populations: implications for the genetic history of North Asia.
    TLDR
    The results of nucleotide diversity analysis in East Asian and Siberian populations suggest that Central and East Asia were the source areas from which the genetically heterogeneous Tuvinians and Buryats first emerged. Expand
    [Structure and diversity of the mitochondrial gene pool of the aboriginal population of Tuva and Buriatia from restriction polymorphism data].
    TLDR
    Analysis of the association between the region V deletion-insertion polymorphism and certain restriction haplogroups pointed to repeated and independent emergence of the 4-bp insertion in Siberia, indicating that the populations Southern and Eastern Siberia can be considered as ancestral relatives to the ethnic groups of the New World. Expand
    [Mitochondrial DNA variation in native inhabitants of Siberia with reconstructions of the evolutional history of the American Indians. Restriction polymorphism].
    TLDR
    The peculiarities of their geographical distribution in Asia allow us to consider the southern regions of Siberia and the adjacent territories of Central and East Asia as the site inhabited by the ancestors of the first wave of migrants to North America. Expand
    The Structure of the Gene Pools of the Ethnic Populations of Altai–Sayan Region Based on of Mitochondrial DNA Polymorphism Data
    Using the data on mitochondrial DNA (mtDNA) polymorphism, genetic structures of the four Turkic-speaking ethnic groups of Altai–Sayan highlands, Southern Altaians (Altai- Kizhi), Khakassians,Expand
    Molecular Genetic Differentiation of the Ethnic Populations of South and East Siberia Based on Mitochondrial DNA Polymorphism
    Using the data on mitochondrial DNA (mtDNA) polymorphism, genetic structures of the ethnic groups inhabiting South and East Siberia, including Altaians, Buryats, Tuvinians, Todjins, Tofalars, Yakuts,Expand
    Mitochondrial DNA analysis in Tibet: implications for the origin of the Tibetan population and its adaptation to high altitude.
    TLDR
    It is suggested that mtDNA mutations are unlikely to play a major role in the adaptation of Tibetans to high altitudes and is supportive of previous genetic evidence that Tibetans, although located in southern Asia, share common ancestral origins with northern Mongoloid populations. Expand
    [Structure of the gene pool of ethnic groups from the Altai-Sayan region from data on mitochondrial polymorphism].
    Using the data on mitochondrial DNA (mtDNA) polymorphism, genetic structures of the four Turkic-speaking ethnic groups of Altai-Sayan highlands, Southern Altaians (Altai-Kizhi), Khakassians,Expand
    Mitochondrial DNA analysis of Mongolian populations and implications for the origin of New World founders.
    TLDR
    It is proposed that indigenous populations in east Central Asia represent the closest genetic link between Old and New World populations and is likely that founder effects manifest throughout Asia and the Americas are responsible for differences in mtDNA haplotype frequencies observed in these regions. Expand
    Asian affinities and continental radiation of the four founding Native American mtDNAs.
    TLDR
    Observations suggest that the process of tribalization began early in the history of the Amerinds, with relatively little intertribal genetic exchange occurring subsequently. Expand
    mtDNA variation of aboriginal Siberians reveals distinct genetic affinities with Native Americans.
    TLDR
    The hypothesis that the first humans to move from Siberia to the Americas carried with them a limited number of founding mtDNAs is supported and that the initial migration occurred between 17,000-34,000 years before present. Expand
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