Mitochondrial DNA Copy Number and Risk of Oral Cancer: A Report from Northeast India

@inproceedings{Mondal2013MitochondrialDC,
  title={Mitochondrial DNA Copy Number and Risk of Oral Cancer: A Report from Northeast India},
  author={Rosy Mondal and Sankar Kumar Ghosh and Javed Hussain Choudhury and Anil Seram and Kavita K Sinha and Marine Hussain and Ruhina Shirin Laskar and Bijuli Rabha and Pradip Peter Dey and Sabitri Ganguli and Monisha NathChoudhury and Fazlur Rahman Talukdar and Biswadeep Chaudhuri and Bishal Dhar},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Oral squamous cell carcinoma (OSCC) is the sixth most common cancer globally. Tobacco consumption and HPV infection, both are the major risk factor for the development of oral cancer and causes mitochondrial dysfunction. Genetic polymorphisms in xenobiotic-metabolizing enzymes modify the effect of environmental exposures, thereby playing a significant role in gene-environment interactions and hence contributing to the individual susceptibility to cancer. Here, we have investigated… CONTINUE READING

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