Mitochondrial Catalase and Oxidative Injury

  title={Mitochondrial Catalase and Oxidative Injury},
  author={J. Bai and A. Cederbaum},
  pages={189 - 199}
  • J. Bai, A. Cederbaum
  • Published 2001
  • Chemistry, Medicine
  • Neurosignals
  • Mitochondria dysfunction induced by reactive oxygen species (ROS) is related to many human diseases and aging. In physiological conditions, the mitochondrial respiratory chain is the major source of ROS. ROS could be reduced by intracellular antioxidant enzymes including superoxide dismutase, glutathione peroxidase and catalase as well as some antioxidant molecules like glutathione and vitamin E. However, in pathological conditions, these antioxidants are often unable to deal with the large… CONTINUE READING
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