Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins

@inproceedings{Uzarska2016MitochondrialBA,
  title={Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins},
  author={Marta A. Uzarska and Veronica Nasta and Benjamin D Weiler and Farah Spantgar and Simone Ciofi-Baffoni and Maria Rosaria Saviello and Leonardo Gonnelli and Ulrich M{\"u}hlenhoff and Lucia Banci and Roland Lill},
  booktitle={eLife},
  year={2016}
}
Assembly of mitochondrial iron-sulfur (Fe/S) proteins is a key process of cells, and defects cause many rare diseases. In the first phase of this pathway, ten Fe/S cluster (ISC) assembly components synthesize and insert [2Fe-2S] clusters. The second phase is dedicated to the assembly of [4Fe-4S] proteins, yet this part is poorly understood. Here, we characterize the BOLA family proteins Bol1 and Bol3 as specific mitochondrial ISC assembly factors that facilitate [4Fe-4S] cluster insertion into… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Fe–S cluster assembly in the supergroup Excavata

JBIC Journal of Biological Inorganic Chemistry • 2018
View 3 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 94 references

Metabolic Disease 37:553–563

A Melber, U Na, +4 authors DR. Winge
2016
View 4 Excerpts
Highly Influenced

2Fe-2S] cluster with cysteinyl and histidyl ligation. Biochemistry 48:9569–9581

H Li, DT Mapolelo, S Randeniya, MK Johnson, CE. Outten
2012
View 5 Excerpts
Highly Influenced

The E

N Yeung, B Gold, +4 authors G. Butland
coli monothiol glutaredoxin GrxD forms homodimeric and heterodimeric FeS cluster containing complexes. Biochemistry 50: 8957–8969. doi: 10.1021/bi2008883 Uzarska et al. eLife 2016;5:e16673. DOI: 10.7554/eLife.16673 • 2011
View 1 Excerpt
Highly Influenced

Similar Papers

Loading similar papers…